You can try something like this,

Code:
Option Explicit
Dim terminate_app As Boolean

Private Sub Form_Load()
    If App.PrevInstance Then
        terminate_app = True
        MsgBox "A copy of My Program is already loaded!", vbInformation
        Unload Me
        Exit Sub
    End If

' YOUR CODE HERE

End Sub


Private Sub Form_QueryUnload(Cancel As Integer, UnloadMode As Integer)
	If terminate_app = True Then Exit Sub ' only run on normal exit

' Stop timers, close open files, save user settings, etc,etc,

End Sub

Private Sub Form_Unload(Cancel As Integer)

    Dim i As Integer
    ' unload forms 
    For i = Forms.Count - 1 To 0 Step -1
        Unload Forms(i)
    Next i
    
    'Set Form1 = Nothing
End Sub