I use edonkey. It's pretty darn good. Has almost all the files but most of the time it takes ages to connect to a user to download a file. But if you are lucky, it can download at about 100KB/S on my Cable which is pretty good compared to Morpheus.
DC is also pretty good but it doesn't have that much stuff on it and most of the time, the user you want to download from doesn't have an extra slots. Its download/upload speed is pretty good though.