If the file was a Random Access File, (All Lines/Records are the Same Length) then you could use the Open.. For Random Access Read Statement and the Get Method to randomly pick a line from the File.

Otherwise, you will need to read the whole file in, parse it into it's individual lines, then seelct one at random, eg.
Code:
Dim iFile As Integer
Dim iPos As Long
Dim sFile As String
dim iLines As Integer
Dim aLines() As String

iFile = FreeFile
Open "C:\MyFile.txt" For Input As iFile
    sFile = Input(LOF(iFile), iFile)
Close iFile
While Len(sFile)
    iPos = Instr(sFile, vbCrLf)
    If iPos = 0 Then iPos = Len(sFile) + 1
    ReDim Preserve aLines(iLines)
    aLines(iLines) = Left(sFile, iPos - 1)
    sFile = Mid$(sFile, iPos + 2)
    iLines = iLines + 1
Wend
Randomize Timer
Msgbox aLines(Int(Rnd * Ubound(aLines)))

------------------
Aaron Young
Analyst Programmer
[email protected]
[email protected]