How to change the specified color in the picture to another color?

[I Love VB6]

Your request now is totally different from your first post. You made it sound like you wanted to change a solid color (red) to another solid color (blue) which is plausible. No, you say you want to take an image that has one or more colors that has been changed automatically back to it's original colors. The only way I can think of is to have a copy of the original image unchanged before the copy takes place and then after the copy process you retrieve this original image and place it in the RTB where the changed image is positioned. This is basically the same thing as Shaggy Hiker suggested in post #4

The question I have now is the data from MS-Word a combination of text and image or just an image only. A problem would be how do you get the image from the source before you transfer the data over to the RTB.

BTW: What causes the image colors to change in the first place? Maybe this might be your problem to be solved