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You'd have to create a NEW instance of the label class:
VB.NET Code:
  1. Dim myLabel As New Label()
Then just set any properties you need and add it to the container you wish to hold it, commonly the form.
VB.NET Code:
  1. myLabel.Text = "Hello world"
  2. myLabel.Location = New Point(30, 30)
  3. Me.Controls.Add(myLabel)