Works fine for me. That said, your code should be:
vb.net Code:
  1. If e.KeyCode = Keys.Right OrElse e.KeyCode = Keys.Down Then TextBox2.Select()
or:
vb.net Code:
  1. Select Case e.KeyCode
  2.     Case Keys.Right, Keys.Down
  3.         TextBox2.Select()
  4. End Select
You should not have two separate If blocks and you should not be calling Focus.