That article is a bit vague - some of the posts on the link indicate that it will run but is not supported - like many old products that fall out of support.

But the flip side of that is many products use MSDE - BackupExec, Sony Vegas Video editing app I have, PC-based phone systems that my customers have - I'm sure it's popping up all over the place.

Just another thing to try to keep clear while upgrading and supporting new installations