If pressing the print screen key is the only way to grab the image. Then, use it. In your program add a timer. In the timer check the clipboard for an image. If there's an image then transfer it to a picturebox,clear the clipboard and then analyze it.

Something like:
VB Code:
  1. Private Sub Timer1_Timer()
  2.     If Clipboard.GetFormat(vbCFBitmap) Then
  3.         Picture1.Picture = Clipboard.GetData(vbCFBitmap)
  4.         Clipboard.Clear
  5.         'analyze picture
  6.     End If
  7. End Sub