Make sure that you have an item selected in your listview:


VB Code:
  1. If  lvResults.SelectedItems.Count > 0 Then
  2.        If e.Button = MouseButtons.Right Then
  3.             Dim lvItem As ListViewItem = lvResults.SelectedItems(0)
  4.             If lvItem.SubItems(1).Text = "" Then
  5.             Else
  6.                 Clipboard.SetDataObject(lvItem.SubItems(1).Text, True)
  7.                 UpdateStatus(lvItem.SubItems(1).Text & " copied to clipboard")
  8.             End If
  9.         End If
  10.   end if

But also listen to apolizoi about adding Try Catch blocks to your code.