Granting that all your menuitems are handled with one sub (which would be wise)....using addHandlers in your Form_Load or menu creation...

VB Code:
  1. AddHandler MyMenuItem.Click, AddressOf MenuClick


You then code a function below that all clicks on the menu are directed to:
VB Code:
  1. Protected Sub MenuClick(ByVal sender As Object, ByVal e As EventArgs)
  2. Select Case CType(sender, MenuItem).Text
  3.  
  4.  Case "Copy"
  5.     'do something or call some function
  6.    
  7.  
  8.  Case "Paste"
  9.    'do something else or call some other function
  10.  
  11. End Select
  12. End Sub