From man's point of view, he should realize that he is insignificant in comparison to God.

From God's point of view, He makes us significant.

It is not man's place to say, "Why have you made me thus?". And you didn't read the verses even though I gave you specific "fish". I know I can't expect you to look it up (but I gave you what you asked for).

Don't worry, there are some that will remain insignificant (from a certain point of view), but even "vessels of destruction" have their significance.

Alot of people (even so-called Christians) fear this possibility of fact.