see the code

Code:
    Dim message As New MailMessage()
                    message.From = New MailAddress("[email protected]")

                    message.[To].Add(New MailAddress("erum@msncom"))
                    'message.[To].Add(New MailAddress("[email protected]"))
                    'message.[To].Add(New MailAddress("[email protected]"))

                    'message.CC.Add(New MailAddress("[email protected]"))
                    'message.Subject = "This is my subject"
                    message.Body = "This is the content"

                    Dim client As New SmtpClient("IRAM-PC")

                    client.Send(message)
i m unable to send email via this code and gives me an exception

Failure sending mail.

System.Net.Mail.SmtpException was unhandled by user code
Message="Failure sending mail."
Source="System"
StackTrace:
at System.Net.Mail.SmtpClient.Send(MailMessage message)
at gfln1.ViewCompany1.Button1_Click(Object sender, EventArgs e) in C:\Users\Iram\Documents\Visual Studio 2008\Projects\gfln1\gfln1\ViewCompany1.aspx.vb:line 108
at System.Web.UI.WebControls.Button.OnClick(EventArgs e)
at System.Web.UI.WebControls.Button.RaisePostBackEvent(String eventArgument)
at System.Web.UI.WebControls.Button.System.Web.UI.IPostBackEventHandler.RaisePostBackEvent(String eventArgument)
at System.Web.UI.Page.RaisePostBackEvent(IPostBackEventHandler sourceControl, String eventArgument)
at System.Web.UI.Page.RaisePostBackEvent(NameValueCollection postData)
at System.Web.UI.Page.ProcessRequestMain(Boolean includeStagesBeforeAsyncPoint, Boolean includeStagesAfterAsyncPoint)
InnerException: System.Net.WebException
Message="Unable to connect to the remote server"
Source="System"
StackTrace:
at System.Net.ServicePoint.GetConnection(PooledStream PooledStream, Object owner, Boolean async, IPAddress& address, Socket& abortSocket, Socket& abortSocket6, Int32 timeout)
at System.Net.PooledStream.Activate(Object owningObject, Boolean async, Int32 timeout, GeneralAsyncDelegate asyncCallback)
at System.Net.PooledStream.Activate(Object owningObject, GeneralAsyncDelegate asyncCallback)
at System.Net.ConnectionPool.GetConnection(Object owningObject, GeneralAsyncDelegate asyncCallback, Int32 creationTimeout)
at System.Net.Mail.SmtpConnection.GetConnection(String host, Int32 port)
at System.Net.Mail.SmtpTransport.GetConnection(String host, Int32 port)
at System.Net.Mail.SmtpClient.GetConnection()
at System.Net.Mail.SmtpClient.Send(MailMessage message)
InnerException: System.Net.Sockets.SocketException
ErrorCode=10061
Message="No connection could be made because the target machine actively refused it 2001:0:4137:9e76:3808:bd63:4b4d:74f7:25"
NativeErrorCode=10061
Source="System"
StackTrace:
at System.Net.Sockets.Socket.DoConnect(EndPoint endPointSnapshot, SocketAddress socketAddress)
at System.Net.Sockets.Socket.InternalConnect(EndPoint remoteEP)
at System.Net.ServicePoint.ConnectSocketInternal(Boolean connectFailure, Socket s4, Socket s6, Socket& socket, IPAddress& address, ConnectSocketState state, IAsyncResult asyncResult, Int32 timeout, Exception& exception)
InnerException: