I have customer/order form.When i delete a record from datagrid.It deletes the record but when i refresh the page or run the app again it comes because i think it just deletes temp from the grid not from the database.How do delete it from the database?

Code:
 Private Sub btndelete_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles btndelete.Click
        'Me.CustomerTableAdapter.Fill(Me.CustomerDataSet.Customer)
        'BindingSource1.Remove(CustomerDataSet.Customer)
        BindingSource1.RemoveCurrent()
     End Sub