Is there a way that you can refresh just one frame and not a whole page?

I have a site with 3 frames. I only want one to be refreshed, is there a way that i can do this?

There is a Top frame, Navigation frame, and a main frame, is there a way that I can use the navigation frame to refresh the main frame, useing the response.redirect "URL" format?? Or is there a way to specify which frame that URL is ment to be opened in?

Thanks

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