[2.0] Could not access file system or registry in vista through programmatically

[R.Pandiarajan]

Hi,
I am developing software product in c#.net 2.0. In Windows XP I can access file system to store product information regardless of the user logged in the system.
Now I want to do it in Vista, But I could not access Registry or file system (E:\Windows\System32).
It showing
UnAuthorizedAccessException

Any solution or any alternative ?
Thanks in advance,
R. Pandiarajan.