I've used VS2005 briefly on my brand new system. My first thoughts:

Vast improvements in ASP.Net.
Cool new dev features (controls, click-once, xml doc).
Healthy framework namespace additions, excluding My which I hate - I much prefer System.Net.NetworkInformation.Ping than the My.Computer.Network.Ping.
MSBuild seems quite versatile.
The documentation seems enhanced to me - however, the document explorer is a hog.
I have 1 GB of RAM but it seems that I'll need another one to work with a couple of VS instances and SQL2005.

Still haven't tested it but I hope the web VSS feature works well - it has been long overdue.

Your thoughts?