I dont think so;

How much ram you have in you machine?
How much TSR's programs you are running in your system?
How big is you Database?

Note: If you have too much TSR's running in you system, it will consume too much ram, so the ram left will be not enouth and the system will have to make the SWAP procedure and this will slow down your system.

Please forgive my English

adcomp - Puerto Rico