is this possible to create application that run from a server with vb6.0?

What does it take to be able to create an app that can be accessed by multiple users on the server?

I have no idea what it takes but my boss (a non-technical person) keeps asking teh why's and why nots.

if this is easier with .NET this would be helpful to know also. I hope to move to .NET by the end of the year.

Thanks!