VB6.0 to VB.Net HELP!!

[Edneeis]

Here is a rought translation to .NET although you could use the Compatiblity namespace to use almost the same code you have there.

Dim filepath As String = "C:\Code\Practice\TestBed9\bin\grades.txt"
 
        'create arrays (or in this case arraylists)
        Dim labs As New ArrayList
        Dim questions As New ArrayList
        Dim tests As New ArrayList
        Dim participations As New ArrayList
 
        'open file
        Dim fs As New IO.FileStream(filepath, FileMode.Open)
        'create reader for file
        Dim sr As New IO.StreamReader(fs)
        'read until there is no more to read
        Do While sr.Peek > -1
            'read one line at a time
            Dim line As String = sr.ReadLine
            'parse into fields
            Dim fields() As String = line.Split(Char.Parse(","))
            'test for student match
            If fields(0) = cboStudent.Text Then 'name
                Select Case fields(1) 'type
                    Case "Lab"
                        labs.Add(fields(2)) 'grade
 
                    Case "Questions"
                        questions.Add(fields(2)) 'grade
 
                    Case "Tests"
                        tests.Add(fields(2)) 'grade
 
                    Case "Participation"
                        participations.Add(fields(2)) 'grade
 
                End Select
            End If
 
        Loop
        'close and release file
        fs.Close()

Also there could be a number of improvements if you wanted to go OOP with it. You could then make a Grades or Student class/collection and just serialize/deserialize it to and from disc. Then there is no parsing required and you can keep the data in memory for faster access.