That's one of the issues with medicine: We know so much that we forget that we don't know even more. This may be particularly true with what you call "lady issues", for whatever reason, but it's true for all of us. For example, I believe that itching is not understood. We all know what it is, we might be able to identify some things that cause it, but we don't know what is actually happening from a medical standpoint. An itch is a feeling that causes us to scratch, which is a definition based on the symptom and not the cause.
It's one of those things. We often don't quite know.

