How to centralise an Application

Is it possible to deploy an application in a LAN Server ONLY and set up other machines to link to the the server and use the application. Or is that what Windows Communication Foundation is about. If so how do you set up the client machines to consume the central application? Just asking.

How are the users on the client machines meant to interact with the application?

What's the point in ONLY deploying on a server (unless it's a terminal server)?