How delete in registry keys instead using Regedit?

Hi, I'm a newbie.
I have problems about USB device drivers: I can see the driver correctly installed but application says device is not present.
I solved using Regedit:
in
HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Enum\USB

I have to manually delete the key

HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Enum\USB\Vid_04d8&Pid_8001

with all subkeys.

I've seen there are several examples managing registry keys using vb, but I can't understand how detect if the key is present and how delete it.
Can anyone explain me?
Thanks.

Take a look here Accessing the Registry with Visual Basic .NET

Read the path to PBrush if the key is located.

Code:

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Private Sub Button1_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Button1.Click
    Dim regVersion As RegistryKey
    regVersion = Registry.LocalMachine.OpenSubKey("SOFTWARE\Microsoft\Windows\CurrentVersion\App Paths\pbrush.exe", True)
    If regVersion Is Nothing Then
        MessageBox.Show("pbrush key does not exists")
    Else
        ' read default value
        MessageBox.Show(String.Concat("Path to pbrush is ", regVersion.GetValue("").ToString))
    End If
End Sub

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To delete a key you need to run your app as an administerator for keys under HKLM

See Permission

In this example KSG1 is a key I created for this demo

Code:

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Dim regVersion As RegistryKey
regVersion = Registry.LocalMachine.OpenSubKey("SOFTWARE\Microsoft\Windows\CurrentVersion\App Paths", True)
If regVersion Is Nothing Then
    MessageBox.Show("KSG1 does not exists")
Else
    Try
        regVersion.DeleteSubKey("KSG1")
        MessageBox.Show("Deleted key")
    Catch ex As Exception
        MessageBox.Show(ex.Message)
    End Try
End If

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