Is it wrong to use Guid's for uniquely refrencing files?

Hi guys,

I am workng on an application that maintains metadata in a database for a user's files. This meta-data can be used for multipule file types that share the same "information" in a logical sense.

My idea is to maintain conformaty in the database by asigning a unique refrence entity to each file that should be logically grouped as using the same meta data.

I was wondering if this would be a good place to implement Guid's or are there better ways to define unique refrences for applications that require them.