Planning Phase, looking for tips

hi everyone. im not sure if this is the right place to post but...im in the begining phase of planning a new software project and was wondering if anyone can give me some pointers on how to best go about it. i have created a web page that will update a MySql database on the internet (im planning on being hosted with yahoo bussiness). the web page will allow people to view the inventory being stored in the db (ie. whats available).
i want to create a program that will have a similar db on the user side, where they can add/remove inventory items. when an internet connection is available, i would have the user side sync up the server side db and update it.

the web side is not a prob as i have experience with MySql and PHP. i just have no experience working with VB connecting to the net. anyone got some ideas?