Using GetPixel on entire screen?

Is there any way to use GetPixel on the screen no matter what programs are shown or desktop? GetPixel needs the handle as the parameter. I just want to know the color of anywhere that is shown on the screen no matter what program it is and not worry about the handle.

Is this possible?

Thanks

VB Code:

Private Declare Function GetDesktopWindow Lib "user32" () As Long
Private Declare Function GetPixel Lib "gdi32" (ByVal hdc As Long, ByVal x As Long, ByVal y As Long) As Long
Private Declare Function GetWindowDC Lib "user32" (ByVal hwnd As Long) As Long
 
Private Sub Command1_Click()
  Dim dhwnd As Long
  Dim dhdc As Long
  Dim color As Long
  Dim x As Long
  Dim y As Long
  
  dhwnd = GetDesktopWindow
  dhdc = GetWindowDC(dhwnd)
  color = GetPixel(dhdc, x, y)
End Sub