Painting in a PictureBox with several colors

I need to pint several parts of a picture box with different colors.
I'm using the ExtFloodFill function.
The question is, do I have to create a new brush every time I need to change the color?
For example, Combo3 has a few colors:

VB Code:

Private Sub Combo3_Click()
    crNewColor = Combo3.List(Combo3.ListIndex)
    DeleteObject mBrush
    mBrush = CreateSolidBrush(crNewColor)
    SelectObject Picture1.hDC, mBrush
End Sub

Is this correct?
Is there any better way?