Configuration problem in VS 2005 ?

Hello everyone, my VS 2005 is fresh install (without 2003 before).
When I try to debug any program, the following error appears:

Error while trying to run project: Unable to start debugging.
The binding handle is invalid.

Even it is a new project with only one form, nothing on it.

I guest there is some problem with the Debug config, 'cause I see there is AnyCPU, x86, x64 in the field next to "Debug" combo box. I tried them out but still doesn't work.

Anyone got experience on this matter, plz tip me, thanks.

(I post here because there is no forum for .NET IDE in general)