Is it possible to create install package by P&D without ST6UNST.LOG file is list?

I understand that ST6UNST.LOG is a neccessary file used for complete application uninstall process.
My point of problem is on, I try to make some setup that most contain only .DLL and neccessary file for run application. Application file and data will be stored on Server site. At this point I think the folder for my application on client site is no need (only ST6UNST.LOG may stored on application directory).

So Is it possible to create install package by P&D without ST6UNST.LOG file is list? (But still aviable for uninstall)
Or Is it possible to create install package by P&D that uninstall process is not need? (Install once and never uninstall)
And How?

Why would you want to install a program that nobody could uninstall? That's a feature of Windows. Most installers adhere to it. You could try posting in the Application Deployment section, but I don't know if you will get an answer.

Using Inno Setup it is possible to instal updates which update the existing uninstaller. Also, you have the option of setting "uninstallabale=no" in Inno's setup and no uninstaller is created - this works pretty good for when you are updating some of your programs private components.