overriding , in use of macros

Is it possible to pass something containing a comma as an argument for a macro?

Some options (there may be more):
1. If the comma is inside parentheses it will not be considered an argument

Code:

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#define macro(args) function args
macro((1,2))

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2. Maybe if you pass the argument as a macro name (not sure if this works)

Code:

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#define argument something, with, a, comma
macro(argument)

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3. If that doesn't work make it a function:

Code:

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#define argument() something, with, a, comma
#define macro(arg) do_something(arg())
macro(argument)

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thanks,
#define COMMA ,
seemed to do the trick.