About Desktop/Taskbar

Hi,
I am running my VB Appln from runservices in Win ME. I written some codings to hide desktop and taskbar inside my program. While my my program is loading, that time desktop and taskbar are showing then hiding. Now, I want to hide these in the registry itself (it should not show while loading). Is any way to do it?
2. If my pc goes abnormally, user may reboot this system, after rebooted system loads windows in "SAFE" mode, that time my program is not loading. I need to run my program even if system starts in "SAFE" mode. any solution?
Thanks in advance.