Check if its program's first run

[ident]

Tbh im not too fussed about 1millisecond and it doesn't look cluttered to me.

It's noise. Noise = bad in my opinion. Why need an extra level of comparison????

I was always taught never compare Boolean properties to True or False in If statements or any other conditional. They're already booleans. It ultimately expands to pseudocode like this:

If (chkShowPreview.Checked = True) = True Then