On my form there are two textboxes called (Subject1) & (detail1)
When using the flowing code without assigning the them to (Application Settings) they work fine and I can set them at run time to left or right. But after assigning them to (Application Settings) the don't seem to be responding to the button click.

Code:
Private Sub Button9_Click(sender As Object, e As EventArgs) Handles Button9.Click
        Subject1.RightToLeft = RightToLeft.Yes
        Subject1.TextAlign = HorizontalAlignment.Right
        Detail1.RightToLeft = RightToLeft.Yes
        Detail1.TextAlign = HorizontalAlignment.Right
    End Sub

Private Sub Button8_Click(sender As Object, e As EventArgs) Handles Button8.Click
        Subject1.RightToLeft = RightToLeft.No
        Subject1.TextAlign = HorizontalAlignment.Left
        Detail1.RightToLeft = RightToLeft.No
        Detail1.TextAlign = HorizontalAlignment.Left
    End Sub
I don't know what exactly is going on ?!!