Difference between standalone and client server based application

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Hi all,
I have developed database applicaiton using VB6.0 and Access. Now im developing the same application with VB6.0 and SQL Server2000.

SQL server will be running in one machine and the users will be accessing the database using the application i developed. my question is when I develop do I have to special consideration on the application?. but at the moment im developing it in my standalone pc. if I install the same application in multiple computers what are the things I have to consider. Please let me know how simply I can understand this concept.

Thanks
MRiz